Sometimes you just need a bowl of pasta that feels like a warm hug. This Creamy Shrimp and Chicken Alfredo Pasta is exactly that. Juicy shrimp, tender chicken, and a velvety garlic-Parmesan cream sauce come together in one skillet for a rich and satisfying dish you’ll want to make again and again.
It’s the perfect recipe when you’re craving something indulgent but still easy enough for a weeknight. Pair it with garlic bread or a side salad, and you’ve got a restaurant-worthy meal right at home.
There’s something extra special about combining both shrimp and chicken in one dish. The shrimp brings a slight sweetness and tender bite, while the chicken adds that hearty, filling comfort we all crave. Together, they turn a simple Alfredo into a next-level pasta dish that feels luxurious without being fussy.
This is also one of those recipes that works year-round. It’s cozy enough for cooler nights when you want something warm and creamy, but still light enough for spring or summer thanks to the bright garlic and fresh parsley. It’s a go-to in my kitchen whenever I need to impress guests or just treat myself to something extra comforting.
How to Make Creamy Shrimp and Chicken Alfredo Pasta
1. Cook the Pasta
Boil pasta in salted water according to package directions. Reserve ½ cup of pasta water, then drain and set aside.
2. Cook the Chicken and Shrimp
In a large skillet, heat olive oil and butter over medium heat. Season chicken with salt and pepper, then cook until golden and cooked through. Remove and set aside. Add shrimp to the same skillet and cook for 1–2 minutes per side, just until pink. Remove and set aside.
3. Make the Alfredo Sauce
In the same pan, sauté garlic until fragrant. Add heavy cream, seasonings, and red pepper flakes (if using). Stir and let the sauce simmer until it thickens slightly, about 3–5 minutes. Add the parmesan cheese.
4. Bring It All Together
Add the cooked pasta to the sauce and toss to coat. If it’s too thick, loosen it up with a splash of reserved pasta water. Add the cooked chicken and shrimp back to the skillet and stir to combine.
5. Serve and Garnish
Top with extra Parmesan and freshly chopped parsley. Serve hot and dig in!
More PASTA Recipes
Tips & Variations
- Lighter version? Swap heavy cream for half-and-half or a mix of cream and chicken broth.
- No shrimp? You can use just chicken, or swap in mushrooms or broccoli for a meatless twist.
- Extra cheesy? Stir in a handful of mozzarella for added creaminess.
- Make it spicy: Add more red pepper flakes or a drizzle of hot sauce to the sauce.
More Pasta Night Favorites
Love this recipe? You’ll also enjoy my Creamy Cajun Shrimp & Grits or Creamy Tuscan Salmon for more cozy, creamy goodness.
Tried this dish? Tag me @evseats so I can see your pasta night masterpiece!
Creamy Shrimp and Chicken Alfredo Pasta
Creamy Shrimp and Chicken Alfredo Pasta made in a delicious homemade Alfredo sauce. This recipe is packed with all the flavors you’ll love!
Ingredients
- 1 lb penne pasta
For the shrimp
- 10 oz shrimp, peeled and deveined (if frozen, thawed)
- 1 Tbsp olive oil
- 1 Tbsp cajun seasoning
- 1 tsp paprika
- Pinch of Salt
- Pinch of freshly ground black pepper
For the Chicken
- 1 and 1/2 Tbsp olive oil
- 1 skinless, boneless chicken breast, cut into 1-inch cubes
- 1/2 – 1 Tbsp Cajun seasoning
For the Alfredo sauce
- ½ cup unsalted butter
- 4 oz. cream cheese, softened to room temperature
- 2 cups (1 pint) heavy cream
- 1 Tbsp Cajun seasoning
- 1/2 tsp salt, or to taste
- 1/2 tsp freshly ground black pepper, or to taste
- 1 and ½ cups freshly grated Parmesan
Instructions
Cook the penne pasta according to package instructions. Drizzle a few drops of oil, toss the pasta, and set to the side.
For the Chicken
- Heat oil in a large skillet over medium heat.
- Meanwhile, season the chicken pieces with salt, pepper and Cajun seasoning, and paprika.
- Once skillet is hot, add the chicken pieces and cook, stirring constantly until chicken is no longer pink; about 5-8 minutes. Remove from the pan and set aside.
For the Shrimp
- In a medium bowl, add shrimp, olive oil, Cajun seasoning, paprika, and a pinch of salt and pepper and toss to combine and coat the shrimp.
- Add shrimp to the hot skillet and cook, stirring constantly until shrimp is pink, about 5 minutes. Remove the shrimp from the pan and set aside.
For the Alfredo Sauce
- In the same skillet, melt the butter over medium-low heat. Once the butter is melted, add the garlic and cream cheese and heat until softened.
- Pour in the milk and add the Cajun seasoning, salt and pepper. Whisk to combine.
- Bring to a low boil. Once boiling, decrease the heat to low and allow the sauce to simmer for 8-10 minutes, whisking occasionally. The sauce should be thick enough to coat a spoon.
- Once sauce has thickened, turn off the heat and add the Parmesan cheese. Stir until cheese is melted and combined. Taste the sauce and adjust the seasonings to your preference.
- Add the penne pasta, shrimp, and chicken to the sauce and toss around to coat evenly. Enjoy!
This is comfort food for sure. So easy to make. Add a glass of wine and this beats going out to dinner hands down.
Super creamy and we loved the cajun spices in this dish.
Yes, Yes and YES!!! Love this recipe and so full of flavor. Easy to make too which is a huge bonus to my life.
My son showed me this recipe on social media and asked me to make it. He loves shrimp and he loves alfredo. And this dish was absolutely delicious! The cajun seasoning is the key ingredient giving this recipe lots of flavor! He asked me to make it again this weekend! So good!
This is surely a festive dish. Picture perfect presentation. A dish my family will love. Shrimps look so tempting and yummy.
This looks like a wonderful dinner! I love that you used the same pot – you’re so right – it really builds in extra flavor.
This is one of my favorite recipes! Creamy shrimp and chicken alfredo pasta is a great way to satisfy my family. Thanks for this highly recommended recipe Evi!
Such a tasty sauce! I substituted dairy-free butter/cream cheese and it turned out great!
That pasta was SO good! And I love how easy it was. Definitely making again soon!
Aaah, this was so creamy! What a treat it was. I wanted to devour it all alone and not share. 😀
Wow! This dish looks absolutely delicious! Shrimp, chicken and pasta are perfect combination that everyone will definitely love! Loved it already!
This dish is as visually impressive as it is tasty. Your guests may want to photograph the meal before the platting begins. I love the Cajun spice and Alfredo sauce. Delicious!
This is on the meal plan for dinner tonight! So happy I came across this post! It looks and sounds delicious! Excited to give it a try!
I love the idea of combining chicken and shrimp in this recipe. A bit like a surf and turf pasta! Looks really good!
This creamy pasta dish looks incredible. I love shrimp and always looking for new ways to cook it.
Chicken and pasta, great combination. Definitely this comfort food and so easy to make.
This was a big hit with my whole family. Even my picky 12 year old loved it. My husband remarked that it was at least a $20 plate at any restaurant. I made the mistake of using Tony Cachere’s Creole Seasoning which contains added salt. It did make my dish very salty so keep that in mind if your seasoning includes salt. I’ll be making this again using a different Cajun seasoning without added salt. I see this being added to our regular rotation.
Thanks Kelsey! Im so glad you and your family loved it!
How much garlic??? I’m not seeing it♀️
Loved the Recipe, and so did the rest of my friends at Potluck. One thing that is missing is the quantity of garlic to be used. It says to add garlic, but in ingredients, it never mentions the quantity of garlic, so I added 2 gloves of garlic to recipe. What is the actual measurement?